Testicular function and morphology after chemotherapy in childhood for ALL
نویسندگان
چکیده
منابع مشابه
Testicular function after combination chemotherapy in childhood for acute lymphoblastic leukaemia.
We have assessed testicular function with luteinising hormone-releasing hormone (LH-RH) and human chorionic gonadotrophin stimulation tests in 44 boys previously treated with, or currently receiving, chemotherapy for acute lymphoblastic leukaemia (ALL). At the same time a testicular biopsy was performed in each boy and the morphology was studied. Histologically the chemotherapy appeared to dama...
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Testicular dysfunction is a common long-term sequela of cytotoxic chemotherapy used in the treatment of many malignancies. The degree to which testicular function is affected is dose- and agent-dependent. The impact on germinal epithelial function of standard multi-agent regimens used in the treatment of lymphomas has been widely studied. Procarbazine-containing regimens result in azoospermia i...
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The effect of quadruple chemotherapy (mustine, vincristine, procarbazine, and prednisolone) on gonadal function was investigated in 15 males and 2 females treated for Hodgkin's disease during childhood. The 2 females have regular menstrual cycles with evidence of ovulation in one. Twelve of the males have shown normal progression of pubertal development since completing their treatment. Nine ou...
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She was followed up regularly for almost two years and showed no signs of relapse. She stopped taking antithyroid drugs several times and suffered brief relapses of hyperthyroidism, but without any psychosis. Comment Hyperthyroidism commonly presents with mental changes such as irritability and anxiety, but psychotic symptoms like hallucination and delusion are rare. The review by Ellis and Mel...
متن کاملImpact of Chemotherapy for Childhood Leukemia on Brain Morphology and Function
OBJECTIVE Using multidisciplinary treatment modalities the majority of children with cancer can be cured but we are increasingly faced with therapy-related toxicities. We studied brain morphology and neurocognitive functions in adolescent and young adult survivors of childhood acute, low and standard risk lymphoblastic leukemia (ALL), which was successfully treated with chemotherapy. We expecte...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1979
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197910000-00069